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Article

Mutation of the PIK3CA oncogene in human cancers.

British journal of cancer - 27 Feb 2006

Karakas B, Bachman K E, Park B H

Abstract excerpt

It is now well established that cancer is a genetic disease and that somatic mutations of oncogenes and tumour suppressor genes are the initiators of the carcinogenic process. The phosphatidylinositol 3-kinase signalling pathway has previously been implicated in tumorigenesis, and evidence over the past year suggests a pivotal role for the phosphatidylinositol 3-kinase catalytic subunit, PIK3CA, in human cancers....

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Identifiers

PMID: 16449998
DOI: 10.1038/sj.bjc.6602970
PMCID: PMC2361173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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