Article
Mutation of the PIK3CA oncogene in human cancers.
British journal of cancer - 27 Feb 2006
Karakas B, Bachman K E, Park B H
Abstract excerpt
It is now well established that cancer is a genetic disease and that somatic mutations of oncogenes and tumour suppressor genes are the initiators of the carcinogenic process. The phosphatidylinositol 3-kinase signalling pathway has previously been implicated in tumorigenesis, and evidence over t...
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