Article
Advances in subunits of PI3K class I in cancer.
Pathology - 1 Apr 2014
Cui Wenli, Cai Ying, Zhou Xiaoyan
Abstract excerpt
Phosphatidylinositol 3-kinases (PI3Ks) include members of a unique and conserved family of intracellular lipid kinases that phosphorylate the 3-hydroxyl group of phosphatidylinositols and phosphoinositides. The resultant activation of many intracellular signalling pathways regulates various biological functions such as cell metabolism, survival, growth, proliferation, polarity, and apoptosis. PI3Ks are classified...
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