Article
COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome.
Psychiatry research - 30 Jul 2010
Shashi Vandana, Howard Timothy D, Keshavan Matcheri S, Kaczorowski Jessica, Berry Margaret N, Schoch Kelly, Spence Edward J, Kwapil Thomas R
Abstract excerpt
The COMT gene is thought to contribute to the cognitive/psychiatric phenotypes in 22q11.2 deletion syndrome. We measured these manifestations against the Val/Met alleles of the COMT gene, in 40 nonpsychotic 22q11DS children. The Val allele was associated with poor IQ, processing speed, executive function and a higher frequency of anxiety disorders, underscoring the importance of the COMT gene in the childhood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.