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Article

Association of COMT and PRODH gene variants with intelligence quotient (IQ) and executive functions in 22q11.2DS subjects.

Journal of psychiatric research - 1 Sept 2014

Carmel Miri, Zarchi Omer, Michaelovsky Elena, Frisch Amos, Patya Miriam, Green Tamar, Gothelf Doron, Weizman Abraham

Abstract excerpt

The 22q11.2 deletion syndrome (22q11.2DS) carries the highest genetic risk factor for the development of schizophrenia. We investigated the association of genetic variants in two schizophrenia candidate genes with executive function (EF) and IQ in 22q11.2DS individuals. Ninety two individuals with 22q11.2 deletion were studied for the genetic association between COMT and PRODH variants and EF and IQ. Subjects...

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Source

Identifiers

PMID: 24853458
DOI: 10.1016/j.jpsychires.2014.04.019

Genes

COMT
PRODH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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