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Article

Maternal prenatal anxiety and child COMT genotype predict working memory and symptoms of ADHD.

PloS one - 1 Jan 2017

O'Donnell Kieran J, Glover Vivette, Lahti Jari, Lahti Marius, Edgar Rachel D, Räikkönen Katri, O'Connor Thomas G

Abstract excerpt

Maternal prenatal anxiety is an important risk factor for altered child neurodevelopment but there is uncertainty concerning the biological mechanisms involved and sources of individual differences in children's responses. We sought to determine the role of functional genetic variation in COMT, which encodes catechol-O-methyltransferase, in the association between maternal prenatal anxiety and child symptoms of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28614354
DOI: 10.1371/journal.pone.0177506
PMCID: PMC5470664

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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