Article
Atrial natriuretic peptide gene promoter polymorphism is associated with left ventricular hypertrophy in hypertension.
Clinical science (London, England : 1979) - 1 Jan 2008
Xue Hao, Wang Shuxia, Wang Hu, Sun Kai, Song Xiaodong, Zhang Weili, Fu Chunyan, Han Yunfeng, Hui Rutai
Abstract excerpt
Recent studies suggest that the ANP (atrial natriuretic peptide)/NPRA (type A natriuretic peptide receptor) system modulates ventricular remodelling and cardiac hypertrophy in hypertension in Western populations. In the present study, we tested for any association between two SNPs (single nucleotide polymorphisms) in the ANP gene (one in the promoter and one exonic) with cardiac hypertrophy. We tested the...
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