Article
Hypertensive left ventricular remodeling and ACE-gene polymorphism.
Cardiovascular research - 1 Jul 1999
Perticone F, Maio R, Cosco C, Ceravolo R, Iacopino S, Chello M, Mastroroberto P, Tramontano D, Mattioli P L
Abstract excerpt
OBJECTIVE: To evaluate the relationship between ACE-gene polymorphism and left ventricular geometry in never treated hypertensives. METHODS: We enrolled 200 hypertensive outpatients that underwent clinical and ambulatory blood pressure measurements, echocardiographic evaluation and analysis for insertion (I)/deletion (D) polymorphism by PCR. Patients with normal or increased (> 125 g/m2 in males and > 110 g/m2 in...
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