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Article

A functional variant of tandem repeats in human telomerase gene was associated with survival of patients with early stages of non-small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2010

Wang Luo, Wang Li-E, Mao Li, Spitz Margaret R, Wei Qingyi

Abstract excerpt

PURPOSE: Elevated levels of human telomerase (hTERT) mRNA in tumors is a marker for poorer survival in patients with stage I non-small cell lung cancer (NSCLC). A functional variant of MNS16A-short tandem repeats in hTERT (S allele) is associated with higher expression levels of hTERT mRNA compared with the MNS16A-long (L) allele. It is unknown, however, whether or not the hTERT MNS16A variant genotype predicts...

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Identifiers

PMID: 20466886
DOI: 10.1158/1078-0432.CCR-10-0269
PMCID: PMC2905469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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