Article
MNS16A tandem repeat minisatellite of human telomerase gene: functional studies in colorectal, lung and prostate cancer.
Oncotarget - 25 Apr 2017
Hofer Philipp, Zöchmeister Cornelia, Behm Christian, Brezina Stefanie, Baierl Andreas, Doriguzzi Angelina, Vanas Vanita, Holzmann Klaus, Sutterlüty-Fall Hedwig, Gsur Andrea
Abstract excerpt
MNS16A, a functional polymorphic tandem repeat minisatellite, is located in the promoter region of an antisense transcript of the human telomerase reverse transcriptase gene. MNS16A promoter activity depends on the variable number of tandem repeats (VNTR) presenting varying numbers of transcription factor binding sites for GATA binding protein 1. Although MNS16A has been investigated in multiple cancer...
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