Article
The (CCTTT)n microsatellite polymorphism in the NOS2 gene may influence lung cancer risk and long-term survival, especially in non-smokers.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2014
Ryk Charlotta, Hou Sai-Mei, Pershagen Göran, Wiklund N Peter, Nyberg Fredrik, de Verdier Petra J
Abstract excerpt
We analyzed the associations of the NOS2 (CCTTT)n promoter polymorphism to lung cancer risk and tumor histology in smokers and non-smokers. We also investigated lung cancer long-term survival in relation to the polymorphism, smoking data, histology, age at diagnosis, and gender. One hundred eighty-five lung-cancer patients and 164 matched controls, where non-smokers were enriched among the lung cancer cases, were...
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