Article
Association of telomerase gene hTERT polymorphism and malignant gliomas.
Journal of neuro-oncology - 1 Sept 2007
Carpentier Catherine, Lejeune Julie, Gros Florent, Everhard Sibille, Marie Yannick, Kaloshi Gentian, Laigle-Donadey Florence, Hoang-Xuan Khe, Delattre Jean-Yves, Sanson Marc
Abstract excerpt
BACKGROUND: The MNS16A polymorphism is located in the downstream region of the hTERT gene and affects telomerase activity. METHODS: MNS16A has been investigated as a potential risk factor and/or prognostic marker for malignant glioma in a cohort of 352 patients (205 glioblastoma, 147 anaplastic g...
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