Article
Prognostic significance of telomerase polymorphism in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2010
Catarino Raquel, Araújo António, Coelho Ana, Gomes Mónica, Nogueira Augusto, Lopes Carlos, Medeiros Rui M
Abstract excerpt
PURPOSE: Lung cancer is the leading cause of death in oncologic patients of western countries, with very low survival rates. Telomerase main components are the catalytic subunit (hTERT) and the RNA template (hTR). A functional polymorphism in the hTERT gene was found in the promoter region (-1327...
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