Article
Polymorphisms in the FAS and FASL genes and survival of early stage non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2009
Park Jae Yong, Lee Won-Kee, Jung Duk-Ku, Choi Jin-Eun, Park Tae-In, Lee Eung-Bae, Cho Sukki, Park Ji-Young, Cha Sung-Ick, Kim Chang-Ho, Kam Sin, Jung Tae Hoon, Jheon Sanghoon
Abstract excerpt
PURPOSE: This study was conducted to investigate the impact of functional polymorphisms in the FAS and FASL genes on the survival of early stage non-small cell lung cancer (NSCLC) patients. EXPERIMENTAL DESIGN: Three hundred and thirty-eight consecutive patients with surgically resected NSCLC were enrolled. The FAS -1377G>A (rs2234767) and -670A>G (rs1800682) and FASL -844C>T (rs763110) polymorphisms were...
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