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Article

Matrix metalloproteinase polymorphisms and survival in stage I non-small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2006

Heist Rebecca Suk, Marshall Ariela L, Liu Geoffrey, Zhou Wei, Su Li, Neuberg Donna, Lynch Thomas J, Wain John, Christiani David C

Abstract excerpt

PURPOSE: The matrix metalloproteinases (MMP) are a family of enzymes that can degrade extracellular matrix and facilitate invasion through the basement membrane. Several polymorphisms in MMP-1, MMP-2, MMP-3, and MMP-12 have been described, some of which lead to differential transcription. We hypothesized that polymorphisms in these MMP genes may be associated with survival outcomes in early-stage non-small cell...

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PMID: 17000679
DOI: 10.1158/1078-0432.CCR-06-0262

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AHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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