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Article

Electrostatic repulsion between HIV-1 capsid proteins modulates hexamer plasticity and in vitro assembly.

Proteins - 1 Jul 2010

Brun Sonia, Chaloin Laurent, Gay Bernard, Bernard Eric, Devaux Christian, Lionne Corinne, Chazal Nathalie, Briant Laurence

Abstract excerpt

Capsid protein (CA) is the major component of the human immunodeficiency virus type 1 (HIV-1) core. Three major phosphorylation sites have been identified at positions S(109), S(149) and S(178) in the amino-acid sequence of CA. Here, we investigated the possible consequences of phosphorylation at these sites on the CA hexamer organization and plasticity using in silico approaches. The biological relevance of...

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Share to Capsid Proteins
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Identifiers

PMID: 20455269
DOI: 10.1002/prot.22729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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