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Article

Assembly properties of the human immunodeficiency virus type 1 CA protein.

Journal of virology - 1 Mar 2004

Ganser-Pornillos Barbie K, von Schwedler Uta K, Stray Kirsten M, Aiken Christopher, Sundquist Wesley I

Abstract excerpt

During retroviral maturation, the CA protein oligomerizes to form a closed capsid that surrounds the viral genome. We have previously identified a series of deleterious surface mutations within human immunodeficiency virus type 1 (HIV-1) CA that alter infectivity, replication, and assembly in vivo. For this study, 27 recombinant CA proteins harboring 34 different mutations were tested for the ability to assemble...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14963157
DOI: 10.1128/jvi.78.5.2545-2552.2004
PMCID: PMC369201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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