Article
Central role of a serine phosphorylation site within duck hepatitis B virus core protein for capsid trafficking and genome release.
The Journal of biological chemistry - 25 Jul 2003
Kock Josef, Kann Michael, Putz Gerhard, Blum Hubert E, Von Weizsacker Fritz
Abstract excerpt
Viral nucleocapsids compartmentalize and protect viral genomes during assembly while they mediate targeted genome release during viral infection. This dual role of the capsid in the viral life cycle must be tightly regulated to ensure efficient virus spread. Here, we used the duck hepatitis B virus (DHBV) infection model to analyze the effects of capsid phosphorylation and hydrogen bond formation. The potential...
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