Article
Ubiquitin-PCNA fusion as a mimic for mono-ubiquitinated PCNA in Schizosaccharomyces pombe.
DNA repair - 1 Jul 2010
Ramasubramanyan Sharada, Coulon Stephane, Fuchs Robert P, Lehmann Alan R, Green Catherine M
Abstract excerpt
Translesion synthesis is a major mechanism with which eukaryotic cells deal with DNA damage during replication. Mono-ubiquitinated PCNA is a key regulator of this process. We have investigated whether a ubiquitin-PCNA fusion can mimic ubiquitinated PCNA, by transforming plasmids expressing this f...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
