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Article

PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}.

Journal of biochemistry - 1 Jul 2009

Suzuki Motoshi, Niimi Atsuko, Limsirichaikul Siripan, Tomida Shuta, Miao Huang Qin, Izuta Shunji, Usukura Jiro, Itoh Yasutomo, Hishida Takashi, Akashi Tomohiro, Nakagawa Yoshiyuki, Kikuchi Akihiko, Pavlov Youri, Murate Takashi, Takahashi Takashi

Abstract excerpt

Translesion DNA synthesis (TLS) involves PCNA mono-ubiquitination and TLS DNA polymerases (pols). Recent evidence has shown that the mono-ubiquitination is induced not only by DNA damage but also by other factors that induce stalling of the DNA replication fork. We studied the effect of spontaneous DNA replication errors on PCNA mono-ubiquitination and TLS induction. In the pol1L868F strain, which expressed an...

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Source

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Identifiers

PMID: 19279190
DOI: 10.1093/jb/mvp043
PMCID: PMC3892766

Genes

PCNA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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