Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication.

doi:10.1093/nar/20.21.5571

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication.

Nucleic acids research - 11 Nov 1992

Coxon A, Maundrell K, Kearsey S E

Abstract excerpt

The cdc21+ gene of Schizosaccharomyces pombe was originally identified in a screen for cdc mutants affecting S phase and nuclear division. Here we show that the cdc21+ gene product belongs to a family of proteins implicated in DNA replication. These include the Saccharomyces cerevisiae MCM2 and MCM3 proteins, which are needed for the efficient function of certain replication origins, and S.cerevisiae CDC46, which...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Cycle Proteins
Chromosomal Proteins, Non-Histone
Chromosomes, Fungal
Cloning, Molecular
DNA Replication
DNA, Fungal
DNA-Binding Proteins
Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Fungal

Humans

Minichromosome Maintenance Complex Component 3

Minichromosome Maintenance Complex Component 4

Molecular Sequence Data

Nuclear Proteins

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 1454522
DOI: 10.1093/nar/20.21.5571
PMCID: PMC334388

Genes

MCM2
MCM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1454522-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication.PMID 1454522Read ↗

The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins.Semantic proximity Read ↗

Fission yeast cdc24(+) encodes a novel replication factor required for chromosome integrity.Semantic proximity Read ↗

The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27.Semantic proximity Read ↗

Characterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints.Semantic proximity Read ↗

A group of interacting yeast DNA replication genes.Semantic proximity Read ↗

mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p.Semantic proximity Read ↗

Reduced dosage of a single fission yeast MCM protein causes genetic instability and S phase delay.Semantic proximity Read ↗

Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality.Semantic proximity Read ↗

CDC6: from DNA replication to cell cycle checkpoints and oncogenesisSemantic proximity Read ↗

Cdm1, the smallest subunit of DNA polymerase d in the fission yeast Schizosaccharomyces pombe, is non-essential for growth and division.Semantic proximity Read ↗

Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication.Semantic proximity Read ↗

A fission yeast homolog of CDC20/p55CDC/Fizzy is required for recovery from DNA damage and genetically interacts with p34cdc2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.