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Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

BMC genomics - 23 Nov 2012

Pan Xian, Lei Bingkun, Zhou Nan, Feng Biwei, Yao Wei, Zhao Xin, Yu Yao, Lu Hong

Abstract excerpt

BACKGROUND: DNA damage response (DDR) plays pivotal roles in maintaining genome integrity and stability. An effective DDR requires the involvement of hundreds of genes that compose a complicated network. Because DDR is highly conserved in evolution, studies in lower eukaryotes can provide valuable information to elucidate the mechanism in higher organisms. Fission yeast (Schizosaccharomyces pombe) has emerged as...

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Identifiers

PMID: 23173672
DOI: 10.1186/1471-2164-13-662
PMCID: PMC3536581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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