CDC44: a putative nucleotide-binding protein required for cell cycle progression that has homology to subunits of replication factor C.

doi:10.1128/mcb.14.1.255-267.1994

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Article

CDC44: a putative nucleotide-binding protein required for cell cycle progression that has homology to subunits of replication factor C.

Molecular and cellular biology - 1 Jan 1994

Howell E A, McAlear M A, Rose D, Holm C

Abstract excerpt

To investigate the means by which a cell regulates the progression of the mitotic cell cycle, we characterized cdc44, a mutation that causes Saccharomyces cerevisiae cells to arrest before mitosis. CDC44 encodes a 96-kDa basic protein with significant homology to a human protein that binds DNA (P...

Topics

Amino Acid Sequence
Base Sequence
Cell Cycle
Cell Cycle Proteins
DNA Replication
DNA, Fungal
DNA-Binding Proteins
Fungal Proteins
Genes, Fungal
Homeodomain Proteins
Humans
Minor Histocompatibility Antigens
Molecular Sequence Data
Mutation
Proto-Oncogene Proteins c-bcl-2

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Identifiers

PMID: 8264593
DOI: 10.1128/mcb.14.1.255-267.1994
PMCID: PMC358375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8264593-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Replication Protein C

Repressor Proteins

Saccharomyces cerevisiae