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Article

CDC44: a putative nucleotide-binding protein required for cell cycle progression that has homology to subunits of replication factor C.

Molecular and cellular biology - 1 Jan 1994

Howell E A, McAlear M A, Rose D, Holm C

Abstract excerpt

To investigate the means by which a cell regulates the progression of the mitotic cell cycle, we characterized cdc44, a mutation that causes Saccharomyces cerevisiae cells to arrest before mitosis. CDC44 encodes a 96-kDa basic protein with significant homology to a human protein that binds DNA (PO-GA) and to three subunits of human replication factor C (also called activator 1). The hypothesis that Cdc44p is...

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Identifiers

PMID: 8264593
DOI: 10.1128/mcb.14.1.255-267.1994
PMCID: PMC358375

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