Article
Fission yeast cdc24(+) encodes a novel replication factor required for chromosome integrity.
Genetics - 1 Jul 1998
Gould K L, Burns C G, Feoktistova A, Hu C P, Pasion S G, Forsburg S L
Abstract excerpt
A mutation within the Schizosaccharomyces pombe cdc24(+) gene was identified previously in a screen for cell division cycle mutants and the cdc24(+) gene was determined to be essential for S phase in this yeast. We have isolated the cdc24(+) gene by complementation of a new temperature-sensitive allele of the gene, cdc24-G1. The DNA sequence predicts the presence of an open reading frame punctuated by six introns...
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