Article
Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence.
Proceedings of the National Academy of Sciences of the United States of America - 18 May 2010
Kinney Justin B, Murugan Anand, Callan Curtis G, Cox Edward C
Abstract excerpt
Cells use protein-DNA and protein-protein interactions to regulate transcription. A biophysical understanding of this process has, however, been limited by the lack of methods for quantitatively characterizing the interactions that occur at specific promoters and enhancers in living cells. Here w...
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