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Article

Reliable prediction of complex phenotypes from a modular design in free energy space: an extensive exploration of the lac operon.

ACS synthetic biology - 18 Oct 2013

Vilar Jose M G, Saiz Leonor

Abstract excerpt

The basic methodology for designing, altering, and constructing biological systems is increasingly relying on well-established engineering principles to move forward from trial and error approaches to reliably predicting the system behavior from the properties of the components and their interact...

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Identifiers

PMID: 23654358
DOI: 10.1021/sb400013w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23654358-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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