Article
Estrogen receptor alpha polymorphisms: correlation with clinicopathological parameters in breast cancer.
Neoplasma - 1 Jan 2010
Anghel A, Raica M, Narita D, Seclaman E, Nicola T, Ursoniu S, Anghel M, Popovici E
Abstract excerpt
Polymorphisms in estrogen receptor alpha gene (ESR1) have been previously associated with breast cancer risk; however, the results were not fully consistent. Our purpose was to study interactions between common genotypes in ESR1, breast cancer risk and tumor phenotypes. 6 ESR1 single nucleotide polymorphisms (SNPs) were genotyped in 103 breast cancer patients and 90 controls using hybridization probes; the...
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