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Article

Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study.

BMC cancer - 6 Nov 2008

Wedrén Sara, Lovmar Lovisa, Humphreys Keith, Magnusson Cecilia, Melhus Håkan, Syvänen Ann-Christine, Kindmark Andreas, Landegren Ulf, Fermér Maria Lagerström, Stiger Fredrik, Persson Ingemar, Baron John A, Weiderpass Elisabete

Abstract excerpt

BACKGROUND: Estrogen is an established endometrial carcinogen. One of the most important mediators of estrogenic action is the estrogen receptor alpha. We have investigated whether polymorphic variation in the estrogen receptor alpha gene (ESR1) is associated with endometrial cancer risk. METHODS: In 702 cases with invasive endometrial cancer and 1563 controls, we genotyped five markers in ESR1 and used logistic...

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Identifiers

PMID: 18990228
DOI: 10.1186/1471-2407-8-322
PMCID: PMC2613912

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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