Article
Impact of ESR1 Polymorphisms on Risk of Breast Cancer in the Chinese Han Population.
Clinical breast cancer - 1 Jun 2021
Yang Wei, He Xue, He Chunjuan, Peng Linna, Xing Shishi, Li Dandan, Wang Li, Jin Tianbo, Yuan Dongya
Abstract excerpt
BACKGROUND: The estrogen receptor-1 (ESR1) gene encodes estrogen receptor-α, which is a major biomarker in the development of breast cancer. This study aimed to investigate the effect of ESR1 polymorphisms on breast cancer in Chinese Han women. MATERIALS AND METHODS: We genotyped 4 candidate single nucleotide polymorphisms (SNPs) in ESR1 among 503 patients with breast cancer and 503 healthy people using the Agena...
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