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Article

Diverse associations between ESR1 polymorphism and breast cancer development and progression.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2010

Ding Shian-ling, Yu Jyh-Cherng, Chen Shou-Tung, Hsu Giu-Cheng, Hsu Huan-Ming, Ho Jar Yi, Lin Yu Hsin, Chang Chien-Ching, Fann Cathy S J, Cheng Chun-Wen, Wu Pei-Ei, Shen Chen-Yang

Abstract excerpt

PURPOSE: To test the hypothesis that polymorphisms of ESR1, the gene encoding estrogen receptor alpha (ERalpha), are associated with susceptibility, clinical phenotype, and progression of breast cancer. PATIENTS AND METHODS: A case-control study was done on 940 patients with incident breast cancer and 1,547 healthy female controls. Fifteen single-nucleotide polymorphisms (SNP) selected from...

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Identifiers

PMID: 20570923
DOI: 10.1158/1078-0432.CCR-09-3092

Genes

ESR1

Provenance

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