Article
Estrogen receptor alpha (ESR1) gene polymorphism (rs2234693 and rs2046210) with breast cancer risk in pashtun population of Khyber Pakhtunkhwa.
Molecular biology reports - 1 Mar 2023
Shahzad Savera, Khan Najeeb Ullah, Sombal Wafa, Shah Rizwan Ullah, Khan Aakif Ullah, Iqbal Aqib, Munir Iqbal
Abstract excerpt
BACKGROUND: Breast cancer susceptibility is greatly influenced by single nucleotide polymorphisms (SNPs) both in penetrance and non-penetrance genes. The Estrogen Receptor Alfa (ESR1- rs2234693 and rs2046210) have been reported as risk factor of breast cancer in different ethnic groups with inconsistent results. In this study the association of ESR1 (rs2234693 and rs2046210) with breast cancer risk was...
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