Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the Estrogen Receptor 1 Polymorphisms rs2046210 and rs9383590 with the Risk, Age at Onset and Prognosis of Breast Cancer.

Cells - 4 Feb 2023

Miedl Heidi, Oswald Denise, Haslinger Isabella, Gstoettner Manuela, Wenzl René, Proestling Katharina, Schneeberger Christian, Yotova Iveta, Schreiber Martin

Abstract excerpt

Estrogen receptor α (ERα), encoded by the ESR1 gene, is a key prognostic and predictive biomarker firmly established in routine diagnostics and as a therapeutic target of breast cancer, and it has a central function in breast cancer biology. Genetic variants at 6q25.1, containing the ESR1 gene, were found to be associated with breast cancer susceptibility. The rs2046210 and rs9383590 single nucleotide variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Age of Onset
Share to Breast Neoplasms
Share to Case-Control Studies
Share to Estrogen Receptor alpha
Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 36831182
DOI: 10.3390/cells12040515
PMCID: PMC9953811

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the Estrogen Receptor 1 Polymorphisms rs2046210 and rs9383590 with the Risk, Age at Onset and Prognosis of Breast Cancer.PMID 36831182Read ↗

Impact of ESR1 Polymorphisms on Risk of Breast Cancer in the Chinese Han Population.Semantic proximity Read ↗

Impact of ESR1 Polymorphisms on Risk of Breast Cancer in the Chinese Han PopulationSemantic proximity Read ↗

Association of ESR1 gene tagging SNPs with breast cancer risk.Semantic proximity Read ↗

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.Semantic proximity Read ↗

Potentially functional polymorphisms in ESR1 and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Estrogen receptor alpha polymorphisms: correlation with clinicopathological parameters in breast cancer.Semantic proximity Read ↗

A common polymorphism near the ESR1 gene is associated with risk of breast cancer: evidence from a case-control study and a meta-analysis.Semantic proximity Read ↗

Estrogen receptor alpha gene polymorphism and breast cancer.Semantic proximity Read ↗

A systematic review of the relationship between polymorphic sites in the estrogen receptor-beta (ESR2) gene and breast cancer risk.Semantic proximity Read ↗

Diverse associations between ESR1 polymorphism and breast cancer development and progression.Semantic proximity Read ↗

Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer.Semantic proximity Read ↗

The association between a novel polymorphism (rs1062577) in ESR1 and breast cancer susceptibility in the Han Chinese women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.