Article
Estrogen receptor alpha gene polymorphism and breast cancer.
Annals of the New York Academy of Sciences - 1 Sept 2008
Siddig Awatif, Mohamed Abdelrahim Osman, Awad Salma, Hassan Ahmed H, Zilahi Erika, Al-Haj Mohammed, Bernsen Roos, Adem Abdu
Abstract excerpt
Estrogen and estrogen receptors play important roles in the proliferation and development of breast cancer. Several genetic alterations identified in the estrogen receptor alpha gene (ESR1) are thought to influence the expression or function of this protein, and many have been evaluated for their role in breast cancer predisposition. The aim of this study was to evaluate the role of the C325G single nucleotide...
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