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Article

Potentially functional polymorphisms in ESR1 and breast cancer risk: a meta-analysis.

Breast cancer research and treatment - 1 May 2010

Li Ni, Dong Jing, Hu Zhibin, Shen Hongbing, Dai Min

Abstract excerpt

Estrogen exposure is a central risk factor in the development of breast cancer. Estrogen receptor alpha (coded by ESR1) is the key mediator of estrogen response in mammary tissue. Genetic changes altering the expression of ESR1 is likely to affect breast cancer susceptibility. Since the identification of several potentially functional polymorphisms in ESR1 (rs2234693, rs9340799, rs1801132, rs3798577, rs2228480),...

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Source

Identifiers

PMID: 19760036
DOI: 10.1007/s10549-009-0532-9

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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