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Article

Mayday sustains trans-synaptic BMP signaling required for synaptic maintenance with age.

eLife - 5 Mar 2021

Sidisky Jessica M, Weaver Daniel, Hussain Sarrah, Okumus Meryem, Caratenuto Russell, Babcock Daniel

Abstract excerpt

Maintaining synaptic structure and function over time is vital for overall nervous system function and survival. The processes that underly synaptic development are well understood. However, the mechanisms responsible for sustaining synapses throughout the lifespan of an organism are poorly understood. Here, we demonstrate that a previously uncharacterized gene, CG31475, regulates synaptic maintenance in adult...

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Identifiers

PMID: 33667157
DOI: 10.7554/eLife.54932
PMCID: PMC7935490

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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