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Article

Dot1a contains three nuclear localization signals and regulates the epithelial Na+ channel (ENaC) at multiple levels.

American journal of physiology. Renal physiology - 1 Jul 2010

Reisenauer Mary Rose, Wang Steven W, Xia Yang, Zhang Wenzheng

Abstract excerpt

We have previously reported that Dot1a is located in the cytoplasm and nucleus (Reisenauer MR, Anderson M, Huang L, Zhang Z, Zhou Q, Kone BC, Morris AP, Lesage GD, Dryer SE, Zhang W. J Biol Chem 284: 35659-35669, 2009), widely expressed in the kidney as detected by its histone H3K79 methyltransferase activity (Zhang W, Hayashizaki Y, Kone BC. Biochem J 377: 641-651, 2004), and involved in transcriptional control...

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Identifiers

PMID: 20427473
DOI: 10.1152/ajprenal.00105.2010
PMCID: PMC2904171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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