Article
Subcellular location of serum- and glucocorticoid-induced kinase-1 in renal and mammary epithelial cells.
American journal of physiology. Cell physiology - 1 May 2007
Cordas Emily, Náray-Fejes-Tóth Anikó, Fejes-Tóth Géza
Abstract excerpt
Serum- and glucocorticoid-induced kinase-1 (SGK1) is involved in aldosterone-induced Na(+) reabsorption by increasing epithelial Na(+) channel (ENaC) activity in cortical collecting duct (CCD) cells, but its exact mechanisms of action are unknown. Although several potential targets such as Nedd4-2 have been described in expression systems, endogenous substrates mediating SGK1's physiological effects remain to be...
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