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Article

Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: a gene polymorphism perspective study.

Therapeutic drug monitoring - 1 Jun 2007

Ebid Abdel-Hameed I Mohammed, Ahmed Mona M M, Mohammed Samah A

Abstract excerpt

This work was performed to explore the effect of polymorphism in multidrug resistant genes on plasma phenytoin levels and patient outcome to evaluate its involvement in drug resistance and toxicity, which is usually associated with antiepileptic drugs. Therefore, we genotyped the adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1) in 100 patients suffering from partial or generalized tonic-clonic...

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Source

Identifiers

PMID: 17529887
DOI: 10.1097/FTD.0b013e318067ce90

Genes

ABCB1

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