Article
Imprinting in the schizophrenia candidate gene GABRB2 encoding GABA(A) receptor β(2) subunit.
Molecular psychiatry - 1 May 2011
Pun F W, Zhao C, Lo W-S, Ng S-K, Tsang S-Y, Nimgaonkar V, Chung W S, Ungvari G S, Xue H
Abstract excerpt
Schizophrenia is a complex genetic disorder, the inheritance pattern of which is likely complicated by epigenetic factors yet to be elucidated. In this study, transmission disequilibrium tests with family trios yielded significant differences between paternal and maternal transmissions of the disease-associated single-nucleotide polymorphism (SNP) rs6556547 and its haplotypes. The minor allele (T) of rs6556547...
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