GABRB2 association with schizophrenia: commonalities and differences between ethnic groups and clinical subtypes.

doi:10.1016/j.biopsych.2006.05.003

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Article

GABRB2 association with schizophrenia: commonalities and differences between ethnic groups and clinical subtypes.

Biological psychiatry - 1 Mar 2007

Lo Wing-Sze, Harano Mutsuo, Gawlik Micha, Yu Zhiliang, Chen Jianhuan, Pun Frank W, Tong Ka-Lok, Zhao Cunyou, Ng Siu-Kin, Tsang Shui-Ying, Uchimura Naohisa, Stober Gerald, Xue Hong

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) and haplotypes in intron 8 of type A gamma-aminobutyric acid (GABA(A)) receptor beta2 subunit gene (GABRB2) were initially found to be associated with schizophrenia in Chinese. This finding was subjected to cross-validation in this study with Japanese (JP) and German Caucasian (GE) subjects. METHODS: Single nucleotide polymorphisms discovery and genotyping were...

Topics

Adult
Aged
Case-Control Studies
Ethnicity
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Germany
Humans
Introns

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Japan

Linkage Disequilibrium

Male

Middle Aged

Polymorphism, Single Nucleotide

Receptors, GABA-A

Schizophrenia

Source

Open in PubMed

Identifiers

PMID: 16950232
DOI: 10.1016/j.biopsych.2006.05.003

Genes

GABRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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