Article
Relationship between GABRB2 gene polymorphisms and schizophrenia susceptibility: a case-control study and in silico analyses.
The International journal of neuroscience - 1 Jun 2022
Heidari Nia Milad, Sargazi Saman, Saravani Ramin, Mirinejad Shekoufeh, Jahantigh Danial, Shakiba Mansoor
Abstract excerpt
PURPOSE: Converging evidence has recently established the significance of γ-aminobutyric acid neurotransmitter (GABA) system in the development of schizophrenia (SCZ). We aimed to determine the association of two markers of the GABAA receptor β2 subunit gene (GABRB2), rs12187676 G/C and rs1816072 T/C, with the risk of SCZ in Iranian population. MATERIALS AND METHODS: In this case-control study, 190 patients with...
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