Article
Positive association of the human GABA-A-receptor beta 2 subunit gene haplotype with schizophrenia in the Chinese Han population.
Biochemical and biophysical research communications - 2 Sept 2005
Liu Jixia, Shi Yongyong, Tang Wei, Guo Tingwei, Li Dawei, Yang Yifeng, Zhao Xinzhi, Wang Hongsheng, Li Xingwang, Feng Guoyin, Gu Niufan, Zhu Shaomin, Liu Huijun, Guo Yangling, Shi Jianguo, Sang Hong, Yan Lijuan, He Lin
Abstract excerpt
A converging body of evidence implicates the gamma-amino butyric acid neurotransmitter system in the pathogenesis of schizophrenia. Recently, Lo et al. reported strong positive association between schizophrenia and GABRB2, demonstrated by single markers and haplotypes of five markers in introns of GABRB2, rs6556547, rs1816071, rs194072, rs252944, and rs187269. To validate this linkage disequilibrium report, we...