Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic regulation on GABRB2 isoforms expression: developmental variations and disruptions in psychotic disorders.

Schizophrenia research - 1 Feb 2012

Zhao Cunyou, Wang Feng, Pun Frank W, Mei Lingling, Ren Lihuan, Yu Zhiliang, Ng Siu-Kin, Chen Jianhuan, Tsang Shui-Ying, Xue Hong

Abstract excerpt

INTRODUCTION: To improve the understanding of psychotic abnormalities and their non-Mendelian inheritance patterns, the epigenetic regulation of the psychotic disorder-associated GABRB2, gene for the type A γ-aminobutyric acid receptor β(2)-subunit, was investigated. METHODS: Expression of GABRB2, and the epigenetic regulatory enzymes histone deacetylases (HDACs) and DNA methyltransferases (DNMTs) in mouse and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Epigenomics

Share to Histone Deacetylases

Share to Postmortem Changes

Share to Receptors, GABA-A

Share to Statistics as Topic

Source

Identifiers

PMID: 22206711
DOI: 10.1016/j.schres.2011.11.029

Genes

GABRB2
DNMT1
HDAC1
HDAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic regulation on GABRB2 isoforms expression: developmental variations and disruptions in psychotic disorders.PMID 22206711Read ↗

GABRB2 in schizophrenia and bipolar disorder: disease association, gene expression and clinical correlations.Semantic proximity Read ↗

DNA methylation regulates gabrb2 mRNA expression: developmental variations and disruptions in l-methionine-induced zebrafish with schizophrenia-like symptoms.Semantic proximity Read ↗

Imprinting in the schizophrenia candidate gene GABRB2 encoding GABA(A) receptor β(2) subunit.Semantic proximity Read ↗

GABRB2, a key player in neuropsychiatric disorders and beyond.Semantic proximity Read ↗

Genetic and epigenetic regulation on the transcription of GABRB2: Genotype-dependent hydroxymethylation and methylation alterations in schizophrenia.Semantic proximity Read ↗

Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders.Semantic proximity Read ↗

Circuit- and Diagnosis-Specific DNA Methylation Changes at γ-Aminobutyric Acid–Related Genes in Postmortem Human Hippocampus in Schizophrenia and Bipolar DisorderSemantic proximity Read ↗

Induced pluripotent stem cell reprogramming-associated methylation at the GABRA2 promoter and chr4p12 GABAA subunit gene expression in the context of alcohol use disorder.Semantic proximity Read ↗

Genome-wide DNA methylation analysis of hippocampal tissue in a murine model of Attention Deficit-Hyperactivity DisorderSemantic proximity Read ↗

Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron-astrocyte-microglia dysregulation.Semantic proximity Read ↗

GAD1 alternative transcripts and DNA methylation in human prefrontal cortex and hippocampus in brain development, schizophrenia.Semantic proximity Read ↗

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.