Article
Distribution of the C1473G polymorphism in tryptophan hydroxylase 2 gene in laboratory and wild mice.
Genes, brain, and behavior - 1 Jul 2010
Osipova D V, Kulikov A V, Mekada K, Yoshiki A, Moshkin M P, Kotenkova E V, Popova N K
Abstract excerpt
The neurotransmitter serotonin is implicated in the regulation of various forms of behavior, including aggression, sexual behavior and stress response. The rate of brain serotonin synthesis is determined by the activity of neuronal-specific enzyme tryptophan hydroxylase 2. The missense C1473G substitution in mouse tryptophan hydroxylase 2 gene has been shown to lower the enzyme activity and brain serotonin level....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.