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Article

Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains.

Genes, brain, and behavior - 1 Nov 2005

Kulikov A V, Osipova D V, Naumenko V S, Popova N K

Abstract excerpt

The brain neurotransmitter serotonin is involved in the regulation of aggressive behavior. The main factor determining the brain serotonin level is the activity of the rate-limiting enzyme in the biosynthesis of the neurotransmitter--tryptophan hydroxylase isoform (TPH) 2 encoded by the Tph2 gene. Recently the C1473G single-nucleotide polymorphism in the Tph2 gene was reported. Here we study the C1473G...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16268992
DOI: 10.1111/j.1601-183X.2005.00145.x

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