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Article

The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains.

Neuroscience letters - 24 Jan 2008

Tenner Katja, Qadri Fatimunnisa, Bert Bettina, Voigt Jörg-Peter, Bader Michael

Abstract excerpt

Tryptophan hydroxylase 2 (TPH2) is the rate limiting enzyme of serotonin synthesis in the brain. A recently described functional (C1473G) single nucleotide polymorphism in mouse TPH2 resulting in vitro in a strongly decreased enzymatic activity was suspected to be responsible for the observed differences in 5-HT levels and behaviour between mice strains. We bred two substrains of C57BL/6 mice carrying the two...

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Source

Identifiers

PMID: 18082956
DOI: 10.1016/j.neulet.2007.11.012

Genes

TPH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains.PMID 18082956Read ↗

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