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Article

Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis.

PloS one - 1 Apr 2010

Auburn Sarah, Fry Andrew E, Clark Taane G, Campino Susana, Diakite Mahamadou, Green Angela, Richardson Anna, Jallow Muminatou, Sisay-Joof Fatou, Pinder Margaret, Molyneux Malcolm E, Taylor Terrie E, Haldar Kasturi, Rockett Kirk A, Kwiatkowski Dominic P

Abstract excerpt

With the functional demonstration of a role in erythrocyte invasion by Plasmodium falciparum parasites, implications in the aetiology of common conditions that prevail in individuals of African origin, and a wealth of pharmacological knowledge, the stimulatory G protein (Gs) signal transduction pathway presents an exciting target for anti-malarial drug intervention. Having previously demonstrated a role for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to GTP-Binding Protein alpha Subunits, Gs

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Source

Open in PubMed Open full text

Identifiers

PMID: 20386734
DOI: 10.1371/journal.pone.0010017
PMCID: PMC2850389

Genes

ADCY9
GNAS
GNB3
RGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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