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Article

Evidence for genetic linkage between a polymorphism in the GNAS gene and malaria in South Indian population.

Acta tropica - 1 Dec 2013

Gupta Himanshu, Sakharwade Sanica C, Angural Arshia, Kotambail Ananthapadmanabha, Bhat Gopal K, Hande Manjunath H, D'Souza Sydney C, Rao Purnima, Kumari Veena, Saadi Abdul V, Satyamoorthy Kapaettu

Abstract excerpt

The complex imprinted GNAS locus which encodes G-alpha subunit (Gαs) is involved in a number of G-protein coupled signaling pathways in eukaryotic cells. Erythrocyte invasion by Plasmodium falciparum parasites is significantly regulated by protein of GNAS gene. This study was designed to evaluate the association between single nucleotide polymorphisms (SNPs) present in GNAS locus and susceptibility to malaria. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23962387
DOI: 10.1016/j.actatropica.2013.08.005

Genes

GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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