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Article

Joint effects of smoking history and APOE genotypes in age-related macular degeneration.

Molecular vision - 4 Nov 2005

Schmidt Silke, Haines Jonathan L, Postel Eric A, Agarwal Anita, Kwan Shu Ying, Gilbert John R, Pericak-Vance Margaret A, Scott William K

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD) is a leading cause of severe visual impairment in older adults worldwide. Cigarette smoking is one of the most consistently identified environmental risk factors for the disease. Several studies have implicated the apolipoprotein E (APOE) gene as modulating AMD risk. The purpose of this study was to investigate whether APOE genotypes modify the smoking-associated...

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Source

Identifiers

PMID: 16288198

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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