Article
The LOC387715 polymorphism and age-related macular degeneration: replication in three case-control samples.
Investigative ophthalmology & visual science - 1 Mar 2007
Ross Robert J, Bojanowski Christine M, Wang Jie Jin, Chew Emily Y, Rochtchina Elena, Ferris Frederick L, Mitchell Paul, Chan Chi-Chao, Tuo Jingsheng
Abstract excerpt
PURPOSE: Age-related macular degeneration (AMD) is a multifactorial blinding disease in the elderly. LOC387715 harbors a single-nucleotide polymorphism that has an association with AMD. This study was conducted to confirm the association between LOC387715 and AMD and to refine estimates of the impact of this gene variation in using samples from three studies: an Australian population-based study and two U.S....
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