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Article

The LOC387715 polymorphism, inflammatory markers, smoking, and age-related macular degeneration. A population-based case-control study.

Ophthalmology - 1 Apr 2008

Wang Jie Jin, Ross Robert J, Tuo Jingsheng, Burlutsky George, Tan Ava G, Chan Chi-Chao, Favaloro Emmanuel J, Williams Andrew, Mitchell Paul

Abstract excerpt

OBJECTIVE: To assess combined effects on the risk of age-related macular degeneration (AMD) by the LOC387715 polymorphism, smoking, and inflammatory or hemostatic factors. DESIGN: Population-based case-control study. PARTICIPANTS: Two hundred seventy-eight AMD cases (224 early, 54 late) and 557 controls matched for age, gender, and smoking, drawn from the Blue Mountains Eye Study cohort. METHODS: Subjects were...

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PMID: 17675241
DOI: 10.1016/j.ophtha.2007.05.038
PMCID: PMC2561271

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